Influences of combining nano zinc, honey and Aloe vera to accelerate healing the wounds caused by third–degree burn in male balb/c mice
نویسندگان
چکیده مقاله:
Introduction: Burns are one of the most common household and industrial injuries. There are evidences which demonstrate the therapeutic properties of honey and Aloe vera. We evaluated the topical influences of this material and nano zinc combination on healing the wounds caused by third-degree burns. Materials and methods: 32 balb/c mice divided into a control group (without treatment), group 1 (treated with Aloe vera and nano zinc), group 2 (treated with Aloe vera, honey and nanoz inc) and group 3 (treated with honey and nano zinc). The third-degree burn was created on the back of balb/c mice with general anesthesia observing sterile conditions. Local treatment of burn was conducted once a week during 6 weeks and after the end of treatment, were anesthetized by ether and then killed. After fixation, the practical steps of general histology technique were performed on it. The samples stained with hematoxylin–eosin and they observed with a microscope. Results: We found full tightening of the burn wound and less scar in the group treated with nano zinc and honey compared to control group and other groups. In histological studies, a significant increase was found in the overall thickness of the skin, keratinocyte layer, the epidermis and hypodermis, number and diameter of the hair follicles in a third group versus other groups. Conclusion: The results showed the organic honey and nano zinc combination accelerate the healing process of burn wound in male balb/c mice. While adding Aloe vera to this composition doesn't have an effect on wound healing.
منابع مشابه
The Healing Effect of Sesame Oil, Camphor and Honey on Second Degree Burn Wounds in Rat
BACKGROUND Many studies were carried out to improve sophisticated dressings to accelerate healing processes and reduce the microbial burden in burn wounds. This study evaluated the healing effect of herbal ointment containing extract of sesame oil, camphor and honey on second degree burn wounds in rats in comparison with daily dressing oil vaseline. METHODS Forty rats were randomly ass...
متن کاملHyperthermia Can Accelerate the Healing Process of 2nd Degree Burn Wounds
The present study aimed at evaluating the effect of local hyperthermia on the healing of burn wounds. Right and Left flunks of 8 Balb-c mice (as treated and control wounds respectively) were burned. Local hyperthermia was applied only for the burn wounds of the right flunks (the treated wound). Sampling was accomplished on the 6th day for half of the mice and on the 9th day for the other half. ...
متن کاملThe Effect of Aloe Vera Gel and Nitrofurazone on Dressing Related Pain of Superficial Burn Wounds
متن کامل
Healing Effect of Aloe Vera on Wound in Albino Mice
Present study is an attempt to investigate wound healing efficiency of Aloe verajuice on excision wound model.This study was undertaken to evaluate the wound healing properties of Aloe vera, for purpose different conc. of Aloe vera juicewere applied with respect toBetadine on excision wound in albino mice.The effect of Aloe vera juice application on excision wound contraction (area in mm 2 ) in...
متن کاملInfluence of Aloe vera on the glycosaminoglycans in the matrix of healing dermal wounds in rats.
The influence of Aloe vera (L.) Burman f. on the glycosaminoglycan (GAG) components of the matrix in a healing wound was studied. Wound healing is a dynamic and complex sequence of events of which the major one is the synthesis of extracellular matrix components. The early stage of wound healing is characterized by the laying down of a provisional matrix, which is then followed by the formation...
متن کاملThe Effect of Aloe Vera Gel and Nitrofurazone on Dressing Related Pain of Superficial Burn Wounds
Burn injuries are a painful form of trauma.1 Patients of burn injuries experience severe pain on a daily basis, both immediately after the injury and during therapeutic procedures, such as dressing changes,debridement and physiotherapy.2 In addition, repetition of these painful procedures often creates anticipatory anxiety forpatients with burns.3 Anxiety induced by a bad acute pain experience ...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ذخیره در منابع من قبلا به منابع من ذحیره شده{@ msg_add @}
عنوان ژورنال
دوره 5 شماره 1
صفحات 38- 46
تاریخ انتشار 2018-01
با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023